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3月26日上午，中南大學(xué)湘雅三醫(yī)院血液內(nèi)科干細(xì)胞采集室內(nèi)，一場特殊的生命傳遞正在進(jìn)行——年僅4歲半的同卵雙胞胎姐妹，在醫(yī)護(hù)人員的陪同下，一邊拿著畫板坐在床上畫畫，一邊通過外周血干細(xì)胞分離機(jī)為身患急性白血病的母親捐獻(xiàn)造血干細(xì)胞。這是該院首次采用兩名低齡雙胞胎同步捐獻(xiàn)外周血干細(xì)胞救治成人患者的案例。

“兒童供者體重通常需達(dá)到受者體重的三分之一以上，但是孩子顯然不達(dá)標(biāo)，于是我們想到了用同一基因型的姐妹倆共同采集。”主治醫(yī)生中南大學(xué)湘雅三醫(yī)院血液內(nèi)科李穎副教授介紹，單靠一個(gè)孩子的干細(xì)胞量不能滿足成人移植需求，而分次采集又可能延誤移植時(shí)機(jī)。

經(jīng)多學(xué)科專家反復(fù)論證，團(tuán)隊(duì)最終決定采用“雙供者聯(lián)合采集”的方案：同步動(dòng)員兩名雙胞胎的造血干細(xì)胞，既不讓孩子重復(fù)采集和穿刺的痛苦，又能及時(shí)的采夠支撐起母親生命的造血干細(xì)胞。

令人動(dòng)容的是，平時(shí)打疫苗也會哭的孩子，因?yàn)橹雷约菏莵?span id="iadureo" class="" lang="EN-US" style="line-height: 1.8; text-indent: 2em; text-align: justify;" data-mce-style="line-height: 1.8; text-indent: 2em; text-align: justify;">“救媽媽”的，在進(jìn)行干細(xì)胞采集時(shí)一聲不吭，態(tài)度特別配合。當(dāng)被問及打針痛不痛時(shí)，孩子輕輕搖頭，“我們一起保護(hù)媽媽”。（來源：新湖南，視頻：向希）

On the morning of March 26, a special life transfer was taking place in the stem cell collection room of the Hematology Department of Xiangya Third Hospital, Central South University. a pair of four and a half years old identical twin sisters sat on a hospital bed, drawing on their sketchpads while donating peripheral hematopoietic stem cells to save their mother battling acute leukemia. This marks the hospital’s first case of two young twins donating stem cells simultaneously to save an adult patient.

Typically, a child donor’s weight should be at least one-third of the recipient’s, but these girls didn’t meet that requirement. So, we decided to collect stem cells from both genetically identical sisters," explained Dr. Li Ying, associate professor at the hospital’s Hematology Department. A single child’s stem cell volume wouldn’t suffice for an adult transplant, while sequential collections could delay treatment.

After thorough discussions with multidisciplinary experts, the medical team opted for a synchronized stem cell mobilization strategy. This method ensured that both girls could donate at the same time, minimizing pain from repeated procedures while providing enough stem cells to support their mother’s recovery.

What moved everyone was how bravely the girls behaved. Though they usually cry during vaccinations, they stayed completely still during the stem cell collection, knowing they were there to "save Mommy." When asked if the needle hurt, one softly shook her head and whispered, "We're protecting Mommy together."（翻譯：潘曉慧）

責(zé)編：潘曉慧

一審：潘曉慧

二審：鄧望軍

三審：譚登